Etiology Unknown: Are less recognized respiratory pathogens associated with a milder course of illness
Authors: Chen, W.J., Foundation for the Advancement of Military Medicine, Arnold, J., Foundation for the Advancement of Military Medicine, Fairchok, M., Foundation for the Advancement of Military Medicine, Schofield, C., Foundation for the Advancement of Military Medicine, Clair, K.J.S., Foundation for the Advancement of Military Medicine, Danaher, P.,Grigorenko, E.
Background. Multiplex assays have greatly enhanced the etiologic determination of acute respiratory infection (ARI). Yet ∼40% of ARI in the multiplex era are test-negative, suggesting that less recognized pathogens account for a significant proportion of illnesses. Evaluating the demographic and clinical characteristics of patients with unknown etiology may help refine clinical management strategies for severe ARI...View More
